Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes

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Date

2006-03

Authors

Alcantara, Luiz Carlos Junior
De Oliveira, Tulio
Gordon, Michelle
Pybus, Oliver G.
Mascarenhas, Rita E.
Seixas, Magda O.
Gonçalves, Marilda
Hlela, Carol
Galvao-Castro, Bernardo

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Publisher

Lippincott Williams & Wilkins

Abstract

We compared the genetic diversity of the Brazilian human T-cell lymphotropic virus type 1 isolates with those found in KwaZulu–Natal (KZN), South Africa, and with the genetic background of the hosts. The seroprevalence rate in KZN was 1.7%. All sequences belonged to the A subgroup. The presence of South African sequences in two different clusters from Brazil, and the finding of the bA-globin haplotype in infected hosts are consistent with the transmission of this virus from Southern Africa to Brazil.

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Keywords

Viral genes

Sustainable Development Goals

Citation

Alcantara, LCJ, De Oliveira, T, Gordon, M, Pybus, OG, Mascarenhas, RE, Seixas, MO, Gonçalves, M, Hlela, C, Cassol, S & Galvão-Castro, B 2006, 'Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes', Aids, vol. 20, no. 5, pp. 780-782. [http://www.aidsonline.com/]

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http://hdl.handle.net/2263/3532

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Media & Communication (Medical Virology)
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