Human papillomavirus DNA in oral squamous cell carcinomas from an African population sample
| dc.contributor.author | Janse van Rensburg, Estrelita | |
| dc.contributor.author | Engelbrecht, Susan | |
| dc.contributor.author | Van Heerden, Willem Francois Petrus | |
| dc.contributor.author | Raubenheimer, E.J. | |
| dc.contributor.author | Schoub, Barry D. | |
| dc.date.accessioned | 2007-07-03T13:52:12Z | |
| dc.date.available | 2007-07-03T13:52:12Z | |
| dc.date.issued | 1996-03 | |
| dc.description | This article was co-written by Prof Janse van Rensburg and Prof Van Heerden before they joined the University of Pretoria. | en |
| dc.description.abstract | BACKGROUND: The incidence of oral squamous cell carcinoma (OSCC) is on the increase in developing countries. MATERIALS AND METHODS: Formalin fixed paraffin embedded blocks of OSCCs from a black South African population sample of peri-urban and rural origin were selected as follows: Group 1 - 57 OSCCs with a mean age of 59 years; Group 2 - 43 OSCCs all cases younger than 40 years; Group 3 - 46 OSCCs with blocks containing only tumour tissue without any normal epithelium and Group 4, a control group of 38 non-neoplastic epithelial lesions. Type specific primers were used in a standard PCR to amplify a segment of the E6 region of HPV 6, 11, 16 and 18. RESULTS: HPV 11 and 16 DNA were found in one sample each from groups 1 and 2 respectively. CONCLUSION: HPV is not an etiologic factor in the development of OSCC in the population studied. | en |
| dc.format.extent | 8503 bytes | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.citation | Van Rensburg, EJ, Engelbrecht, S, Van Heerden, WFP, Raubenheimer, EJ & Schoub, BD 1996, 'Human papillomavirus DNA in oral squamous cell carcinomas from an African population sample', Anticancer Research, vol. 16, no. 2, pp. 969-973. [http://www.iiar-anticancer.org/research/research_index.htm] | en |
| dc.identifier.issn | 0250-7005 | |
| dc.identifier.uri | http://hdl.handle.net/2263/2867 | |
| dc.language.iso | en | en |
| dc.publisher | International Institute of Anticancer Research | en |
| dc.rights | International Institute of Anticancer Research. The publisher prohibits open access to the full text of this article. | en |
| dc.subject | Oral squamous cell carcinoma | en |
| dc.subject | Developing countries | en |
| dc.subject.lcsh | Mouth -- Cancer -- Blacks -- South Africa | |
| dc.subject.lcsh | Papillomaviruses -- South Africa | |
| dc.title | Human papillomavirus DNA in oral squamous cell carcinomas from an African population sample | en |
| dc.type | Article | en |