Actinium-225-PSMA radioligand therapy of metastatic castration-resistant prostate cancer (WARMTH Act) : a multicentre, retrospective study

dc.contributor.authorSathekge, Mike Machaba
dc.contributor.authorLawal, Ismaheel Opeyemi
dc.contributor.authorBal, Chandrasekhar
dc.contributor.authorBruchertseifer, Frank
dc.contributor.authorBallal, Sajana
dc.contributor.authorCardaci, Giuseppe
dc.contributor.authorDavis, Cindy
dc.contributor.authorEiber, Mathias
dc.contributor.authorHekimsoy, Türkay
dc.contributor.authorKnoesen, Otto
dc.contributor.authorKratochwil, Clemens
dc.contributor.authorLenzo, Nat P.
dc.contributor.authorMahapane, Johncy
dc.contributor.authorMaserumule, Letjie C.
dc.contributor.authorMdlophane, Amanda H.
dc.contributor.authorMokoala, Kgomotso M.G.
dc.contributor.authorNdlovu, Honest
dc.contributor.authorPant, Vineet
dc.contributor.authorRathke, Hendrik
dc.contributor.authorReed, Janet D.
dc.contributor.authorSen, Ishita B.
dc.contributor.authorSingh, Aviral
dc.contributor.authorSood, Ashwani
dc.contributor.authorTauber, Robert
dc.contributor.authorThakral, Parul
dc.contributor.authorYadav, Madhav Prasad
dc.contributor.authorMorgenstern, Alfred
dc.contributor.emailmike.sathekge@up.ac.za
dc.date.accessioned2025-09-08T12:55:07Z
dc.date.available2025-09-08T12:55:07Z
dc.date.issued2024-02
dc.descriptionDATA SHARING : The de-identified individual-level patient data, data dictionary, and protocol for this study can be provided to researchers upon written request 24–36 months after publication of the Article. Please send enquiries to the corresponding author. A detailed proposal for how the data will be used is required and we will assess applications on a case-by-case basis, and only for the purpose of individual participant data meta-analysis. A data access agreement must be signed for these data to be released.
dc.description.abstractPlease read abstract in the article.
dc.description.departmentNuclear Medicine
dc.description.departmentRadiography
dc.description.librarianhj2025
dc.description.sdgSDG-03: Good health and well-being
dc.description.urihttp://www.thelancet.com/oncology
dc.emailmike.sathekge@up.ac.za
dc.identifier.citationSathekge, M.M., Lawal, I.O., Bal, C. et al. 2024, 'Actinium-225-PSMA radioligand therapy of metastatic castration-resistant prostate cancer (WARMTH Act) : a multicentre, retrospective study', Lancet Oncology, vol. 25, no. 2, pp. 175-183, doi : 10.1016/S1470-2045(23)00638-1.
dc.identifier.issn1470-2045 (print)
dc.identifier.issn1474-5488 (online)
dc.identifier.other10.1016/S1470-2045(23)00638-1
dc.identifier.urihttp://hdl.handle.net/2263/104248
dc.language.isoen
dc.publisherElsevier
dc.rights© 2024 All rights are reserved, including those for text and data mining, AI training, and similar technologies, including those for text and data mining, AI training, and similar technologies. Notice : this is the author’s version of a work that was accepted for publication in Lancet Oncology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Lancet Oncology, vol. 25, no. 2, pp. 175-183, 2024, doi : 10.1016/S1470-2045(23)00638-1.
dc.subjectProstate-specific membrane antigen (PSMA)
dc.subjectActinium-225
dc.subjectRadioligand therapy (RLT)
dc.subjectMetastatic castration-resistant prostate cancer (mCRPC)
dc.subjectSafety
dc.subjectAntitumour activity
dc.titleActinium-225-PSMA radioligand therapy of metastatic castration-resistant prostate cancer (WARMTH Act) : a multicentre, retrospective study
dc.typePostprint Article

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