Title page for ETD etd-11212012-125807

Document Type Master's Dissertation
Author Davis, Anthony John
Email anthonydavis@telkomsa.net
URN etd-11212012-125807
Document Title Serological response to early vaccination against Babesia bovis and Babesia bigemina in dairy calves
Degree MSc
Department Veterinary Tropical Diseases
Advisor Name Title
Dr J E Crafford Co-Supervisor
Prof A A Latif Co-Supervisor
Prof B L Penzhorn Supervisor
  • Babesia bovis
  • early vaccination
  • dairy calves
  • Babesia bigemina
Date 2012-09-07
Availability unrestricted
Calves infected with Babesia bovis or Babesia bigemina between 3 and 9 months of age can develop immunity without showing overt clinical signs. This transient immunity is not dependent on maternal immunity. After 9 months of age, they are fully susceptible to challenge. Dairy calves between 2 and 3 months of age were vaccinated with B. bigemina and B. bovis live frozen vaccines (Onderstepoort Biological Products®). Two months after vaccination, 90% of calves were serologically positive on IFA test to B. bigemina, and 70% were serologically positive to B. bovis. At this age, only 17% of the control group had seroconverted to B. bigemina and none of the calves had seroconverted to B. bovis. All experimental calves maintained positive serological status to both B. bovisB. bigemina for at least 5 months after vaccination. It is sound practice to vaccinate dairy calves against babesiosis at 2–3 months of age. Endemic stability is achieved before the period of natural resistance wanes.

Copyright © 2011, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria

Please cite as follows:

Davis, AJ 2011, Serological response to early vaccination against Babesia bovis and Babesia bigemina in dairy calves, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://upetd.up.ac.za/thesis/available/etd-11212012-125807 / >


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