Title page for ETD etd-08062008-081742


Document Type Master's Dissertation
Author Nell, Margo Judith
Email margo.nell@med.up.ac.za
URN etd-08062008-081742
Document Title The anti-tumour properties of novel gold compounds
Degree MSc
Department Pharmacology
Supervisor
Advisor Name Title
Prof C E Medlen Supervisor
Keywords
  • human cervical carcinoma cells
  • tumour cells
  • anti-tumour properties
Date 2008-04-23
Availability unrestricted
Abstract
Since the introduction of Auranofin in 1985 there has been no new clinically approved gold containing drugs introduced. Although promising results were achieved with a gold(I) phosphine complex [Au(dppe) 2]Cl (Hoke et al., 1991; Mckeage et al., 2002), this compound was never entered into clinical trials due to i