Title page for ETD etd-01032011-154550


Document Type Master's Dissertation
Author Viljoen, Adrienne
Email adrienne.viljoen@up.ac.za
URN etd-01032011-154550
Document Title Changes in cardiac troponin I concentration and echocardiographic parameters after semen collection in stallions
Degree MSc
Department Companion Animal Clinical Studies
Supervisor
Advisor Name Title
Prof A Carstens Co-Supervisor
Prof M N Saulez Supervisor
Keywords
  • cardiac telemetry
  • heart rate
  • biomarker
  • breeding
  • stallion
  • myocardium
  • cardiac troponin I
Date 2010-11-26
Availability unrestricted
Abstract
This dissertation focuses on the effect of breeding on the myocardium of stallions using cardiac troponin I (cTnI) as the preferred blood biomarker for detection of myocardial cell injury. Haematological, echocardiographic and heart rate (HR) parameters are also reported.

Fourteen clinically healthy phantom-trained stallions were assessed. Cardiac troponin I concentration was determined pre-semen collection and at 4, 6, 12 and 24 hours following semen collection. Predictors that were measured included mean HR during each stage of semen collection, maximum HR, area under the curve for HR and fractional shortening (FS).

Pre-semen collection cTnI concentrations were within reported reference ranges for all stallions. Following semen collection, cTnI concentration was significantly increased at 4 and 6 hours post-semen collection. Results also suggest that the HR of stallions peak during mounting of the phantom. Five stallions failed to show an expected increase in FS immediately post-semen collection. No association was identified between the measured predictors and increased cTnI concentration.

This study concluded that cTnI concentration may increase in stallions following semen collection although the clinical significance of this observed increase in healthy stallions is unclear without histopathological evaluation of the myocardium. No conclusion regarding FS immediately post-semen collection could be drawn from results in this study. The research reported in this dissertation can serve as a reference for future studies investigating cTnI concentrations in stallions.

2010 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria

Please cite as follows:

Viljoen, A 2010, Changes in cardiac troponin I concentration and echocardiographic parameters after semen collection in stallions, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://upetd.up.ac.za/thesis/available/etd-01032011-154550 / >

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